Article
Next-generation sequencing study identifies the first genes associated with Alzheimer's disease in Bangladeshi population: The CARED study.
Journal of Alzheimer's disease : JAD - 1 Mar 2026
Hakim Maliha, Ranjan Redoy, Ken-Dror Gie, Yusuf Md Abdullah, Uddin Mohammad Nur, Mamun Mim Tanzila, Al Mamun Alif, Kawnayn Ghulam, Sharma Pankaj
Abstract excerpt
BackgroundAlthough the molecular basis of Alzheimer's disease (AD) is often studied in Caucasians, its genetic basis in Bangladesh remains elusive.ObjectiveWe explored the association between single-nucleotide variants (SNVs) of Apolipoprotein E (APOE) and other genes for AD risk among Bangladeshis.MethodsWe recruited AD patients and controls aged ≥18 years and conducted next generation sequencing (NGS) to...
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