Article
Generation of a human iPSC line (MPIi008-A) from a patient with Denys-Drash syndrome.
Stem cell research - 1 Jul 2022
Doeser Markus C, Krygin Julia, Röpke Albrecht, Han Dong, Wedlich-Söldner Roland, Schöler Hans R, Pavenstädt Hermann, Kim Kee-Pyo
Abstract excerpt
An induced pluripotent stem cell (hiPSC) line (MPIi008-A) was generated from fibroblasts of a 1-year-old male patient with Denys-Drash syndrome using lentiviral delivery of reprogramming factors OCT4, SOX2, KLF4 and c-MYC. The MPIi008-A iPSC line exhibited typical iPSC morphology and normal karyotype, expressed pluripotent stem cell markers, and showed developmental potential to differentiate into derivatives of...
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