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Article

Oxytocin receptor (OXTR) does not play a major role in the aetiology of autism: genetic and molecular studies.

Neuroscience letters - 3 May 2010

Tansey Katherine E, Brookes Keeley J, Hill Matthew J, Cochrane Lynne E, Gill Michael, Skuse David, Correia Catarina, Vicente Astrid, Kent Lindsey, Gallagher Louise, Anney Richard J L

Abstract excerpt

Oxytocin (OXT) has been hypothesized to play a role in aetiology of autism based on a demonstrated involvement in the regulation of social behaviours. It is postulated that OXT reduces activation of the amygdala, inhibiting social anxiety, indicating a neural mechanism for the effects of OXT in social cognition. Genetic variation at the oxytocin receptor gene (OXTR) has been reported to be associated with autism....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20303388
DOI: 10.1016/j.neulet.2010.03.035

Genes

OXTR
OXT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Oxytocin receptor (OXTR) does not play a major role in the aetiology of autism: genetic and molecular studies.PMID 20303388Read ↗

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