Article
Simultaneous Assessment of Genetic and Epigenetic Contributions to the Plasma Lipid Levels with Respect to Cardiovascular Risk.
Journal of atherosclerosis and thrombosis - 1 Jun 2026
Takeuchi Fumihiko, Yamamoto Masaya, Nakatochi Masahiro, Takano Kozue, Okazaki Atsuko, Emoto Sakurako, Tabara Yasuharu, Katsuya Tomohiro, Yamamoto Ken, Isono Masato, Mori Kotaro, Matsubara Tatsuaki, Ichihara Sahoko, Yokota Mitsuhiro, Hara Hisao, Hiroi Yukio, Kato Norihiro
Abstract excerpt
AIMS: This study aimed to develop a model to simultaneously assess the genetic and epigenetic contributions to plasma lipids. METHODS: The study used two cardiovascular risk groups: individuals with high low-density lipoprotein cholesterol (LDL-C) levels (N = 296) and coronary artery disease (CAD) (N = 315), in contrast to the reference (max N = 3,801) and non-CAD individuals (N = 164). For genetic...
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