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Article

Decoding SARS-CoV-2 variant functionality: balancing innovation and ethical oversight.

Gene - 5 May 2026

Yang Jingjing, An Lei

Abstract excerpt

This letter discusses the application of deep mutation scanning (DMS) on virus saturated variation, with a particular focus on the impact of variants of unknown significance (VUS). This topic also presents challenges in interpreting the functional consequences of VUS. This discussion aims to highlight both the potential and limitations of DMS in the context of virus research.

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Identifiers

PMID: 41707794
DOI: 10.1016/j.gene.2026.150059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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