Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resistance profile of the Plasmodium falciparum dihydropteroate synthase gene in three hospitals in the city of Ndjamena, Chad.

Scientific reports - 17 Feb 2026

Cedric Yamssi, Djakbé Dayang Louis, Ngaryedji Tordibaye, Nadia Noumedem Anangmo Christelle, Pacome Tchuenkam Kom, Anaud Noumedem Kenfack Jaurès, Esther Djeussi Doriane, Alain Djam Chefor, Ismail Ismail Abdel-Kerim, Saleh Barka, Abel Djobo, Hu Haibo

Abstract excerpt

Malaria is a potentially fatal febrile hemolytic parasitic disease caused by Plasmodium species. The objective of this study was to determine the genetic resistance profile of the Plasmodium falciparum dihydropteroate synthase (Pfdhps) gene in three health facilities in the city of N’Djamena. This was a cross-sectional analytical study. Samples were collected from 220 consenting patients. Plasmodium falciparum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials
Share to Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dihydropteroate Synthase

Share to Drug Resistance

Share to Malaria, Falciparum

Share to Plasmodium falciparum

Share to Polymorphism, Restriction Fragment Length

Share to Protozoan Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 41702996
DOI: 10.1038/s41598-026-39796-7
PMCID: PMC13004865

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 16 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resistance profile of the Plasmodium falciparum dihydropteroate synthase gene in three hospitals in the city of Ndjamena, Chad.PMID 41702996Read ↗

Distribution pattern of amino acid mutations in chloroquine and antifolate drug resistance associated genes in complicated and uncomplicated Plasmodium vivax isolates from Chandigarh, North India.Semantic proximity Read ↗

Frequencies distribution of dihydrofolate reductase and dihydropteroate synthetase mutant alleles associated with sulfadoxine-pyrimethamine resistance in Plasmodium falciparum population from Hadhramout Governorate, Yemen.Semantic proximity Read ↗

Distribution of Mutations Associated with Antifolate and Chloroquine Resistance among Imported Plasmodium vivax in the State of Qatar.Semantic proximity Read ↗

Molecular epidemiology of Plasmodium vivax anti-folate resistance in India.Semantic proximity Read ↗

Trends in drug resistance codons in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Kenyan parasites from 2008 to 2012Semantic proximity Read ↗

Surveillance of molecular markers of antimalarial drug resistance in Plasmodium falciparum and Plasmodium vivax in Federally Administered Tribal Area (FATA), Pakistan.Semantic proximity Read ↗

Mutational profile of pfdhfr, pfdhps, pfmdr1, pfcrt and pfk13 genes of P. falciparum associated with resistance to different antimalarial drugs in Osun state, southwestern NigeriaSemantic proximity Read ↗

Polymorphism of Antifolate Drug Resistance in Plasmodium vivax From Local Residents and Migrant Workers Returned From the China-Myanmar Border.Semantic proximity Read ↗

Low prevalence of dihydro folate reductase (dhfr) and dihydropteroate synthase (dhps) quadruple and quintuple mutant alleles associated with SP resistance in Plasmodium vivax isolates of West Bengal, India.Semantic proximity Read ↗

Clinical and molecular monitoring of Plasmodium falciparum resistance to antimalarial drug (artesunate+sulphadoxine-pyrimethamine) in two highly malarious district of Madhya Pradesh, Central India from 2012-2014.Semantic proximity Read ↗

Characterization of Plasmodium falciparum genes associated with drug resistance in Hodh Elgharbi, a malaria hotspot near Malian-Mauritanian border.Semantic proximity Read ↗

Antimalarial Drug Resistance and Novel Targets for Antimalarial Drug DiscoverySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.