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Article

Norepinephrine stress reactivity links to a lipid-rich coronary fat phenotype in humans: a cross-sectional study.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Mar 2026

von Känel Roland, Albertini Tobia, Holzgang Sarah A, Princip Mary, Giannopoulos Andreas A, Buechel Ronny R, Sivakumar Sinthujan, Zuccarella-Hackl Claudia, Pazhenkottil Aju P

Abstract excerpt

Pericoronary adipose tissue (PCAT) attenuation from coronary computed tomography angiography (CCTA) is an imaging biomarker of coronary inflammation. Experimental evidence suggests that sympathetic activation and norepinephrine (NE) can alter perivascular adipose tissue (PVAT) composition. Whether NE stress reactivity relates to PVAT phenotype, as reflected by PCAT attenuation, or varies by chronic stress...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41697119
DOI: 10.1152/japplphysiol.01168.2025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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