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Article

Phenotyping atherosclerotic plaque and perivascular adipose tissue: signalling pathways and clinical biomarkers in atherosclerosis.

Nature reviews. Cardiology - 1 Jun 2025

Grodecki Kajetan, Geers Jolien, Kwiecinski Jacek, Lin Andrew, Slipczuk Leandro, Slomka Piotr J, Dweck Marc R, Nerlekar Nitesh, Williams Michelle C, Berman Daniel, Marwick Thomas, Newby David E, Dey Damini

Abstract excerpt

Computed tomography coronary angiography provides a non-invasive evaluation of coronary artery disease that includes phenotyping of atherosclerotic plaques and the surrounding perivascular adipose tissue (PVAT). Image analysis techniques have been developed to quantify atherosclerotic plaque burden and morphology as well as the associated PVAT attenuation, and emerging radiomic approaches can add further...

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Identifiers

PMID: 39743563
DOI: 10.1038/s41569-024-01110-1
PMCID: PMC12092191

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