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Article

A Mendelian randomization study exploring the genetic associations between biliary system disorders and brain structural changes.

Medicine - 13 Feb 2026

Qu Run, Ruan Qingfen, Han Ruiqin, Li Canmei, Zhao Yanhong, Liang Yi, Zhang Yuzhe

Abstract excerpt

The objective was to evaluate potential genetic associations between biliary system disorders and cortical and subcortical brain structural changes using Mendelian randomization analyses. This study focused on 4 diseases, including primary sclerosing cholangitis, cholecystitis, intrahepatic cholangiocarcinoma, and gallstone disease, and total bilirubin levels as indicators of biliary system disorders. Genome-wide...

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Identifiers

PMID: 41686633
DOI: 10.1097/MD.0000000000047616
PMCID: PMC12908830

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PTH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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