Article
Causal relationships between antibody-induced immune responses and sepsis: Evidence from genetic studies.
Medicine - 13 Feb 2026
Li Liqun, Liu Lijian, Yan Jing, Tan Jinjing, Xie Sheng
Abstract excerpt
The causal relationships between antibody-induced immune responses and the occurrence and mortality of sepsis remain controversial. The 2-sample Mendelian randomization (MR) approach was utilized to reveal the causal associations, along with the potential mediation effects of inflammatory cytokines. The causal associations were analyzed by a 2-sample bidirectional MR analysis, primarily using the inverse variance...
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