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Article

Interaction of fluoride exposure and CREB1 gene polymorphisms on thyroid function in school-age children.

Chemosphere - 1 Sept 2022

Xu Kaihong, Feng Zichen, Afrim Francis Kojo, Ma Jun, Yang Shuo, Zhang Xuanyin, Niu Zeyuan, An Ning, Du Yuhui, Yu Fangfang, Zhou Guoyu, Ba Yue

Abstract excerpt

OBJECTIVES: To evaluate the effects of CREB1 gene polymorphisms and long-term exposure to fluoride on thyroid function of children. STUDY DESIGN: A total of 424 children (including 226 boys and 198 girls) aged 7-12 years old were enrolled in Kaifeng, China by cross-sectional study in 2017. The concentrations of urinary fluoride (UF) and creatinine (UCr) were measured using fluoride ion-selective electrode assay...

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PMID: 35640685
DOI: 10.1016/j.chemosphere.2022.135156

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