Article
Graph-based pangenome reveals structural variation dynamics during cucumber breeding.
Nature genetics - 1 Mar 2026
Zhao Xuebo, Yu Jingyin, Zhang Jie, Sun Honghe, Wu Shan, Zhao Jiantao, Zhou Yao, Hammar Sue A, Lin Ying-Chen, Zhang Zhonghua, Huang Sanwen, Dymerski Ronald T, Chen Feifan, Weng Yiqun, Grumet Rebecca, Xu Yong, Fei Zhangjun
Abstract excerpt
Structural variants (SVs) represent an important yet underexplored component of plant genome diversity. Here we present a graph-based cucumber pangenome constructed from 39 reference-quality genomes, including 27 newly assembled and 12 previously published. The pangenome captures 171,892 high-confidence SVs, which were genotyped across 447 wild and cultivated accessions. Our analyses reveal that, during cucumber...
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