Redefining endometrial cancer phenotypes in the era of molecular classification and sentinel lymph node mapping: results from a multicenter Italian study.

doi:10.1016/j.ijgc.2026.104502

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Article

Redefining endometrial cancer phenotypes in the era of molecular classification and sentinel lymph node mapping: results from a multicenter Italian study.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Sept 2026

Scarpelli Elisa, Capozzi Vito Andrea, Perrone Emanuele, Palmieri Emilia, Bogani Giorgio, De Iaco Pierandrea, Perrone Anna Myriam, Chiantera Vito, Cucinella Giuseppe, Gaiano Michela, Carnelli Marco, Puppo Andrea, Uccella Stefano, Ceccaroni Marcello, Restaino Stefano, Vizzielli Giuseppe, Fanfani Francesco, Berretta Roberto

Abstract excerpt

OBJECTIVE: To describe the clinicopathologic phenotypes of endometrial cancer across molecular sub-types and to identify independent predictors of nodal metastasis and sentinel lymph node (SLN) mapping failure. METHODS: This multicenter retrospective study included 2592 endometrial cancer patients with defined molecular classification and SLN mapping. Continuous variables are reported as medians. Tumors were...

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Topics

Humans
Female
Endometrial Neoplasms
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Retrospective Studies

Phenotype

Aged

Lymphatic Metastasis

Sentinel Lymph Node

Sentinel Lymph Node Biopsy

Italy

Adult

Aged, 80 and over

Source

Open in PubMed

Identifiers

PMID: 41667298
DOI: 10.1016/j.ijgc.2026.104502

Genes

SLN
POLE

Provenance

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