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Article

Investigation of leptin and leptin receptor gene polymorphisms in schizophrenia: further support for an association with attempted suicide.

Acta neuropsychiatrica - 10 Feb 2026

Aytac Hasan Mervan, Oyaci Yasemin, Aytac Eren, Pehlivan Mustafa, Burhan Huseyin Sehit, Alptekin Furkan Bahadir, Pehlivan Sacide

Abstract excerpt

OBJECTIVE: This study aimed to investigate leptin (LEP) (G-2548A) and leptin receptor (LEPR) (668A>G) gene polymorphisms in schizophrenia patients with and without suicide attempts, compared to controls. METHODS: The study included 120 patients with schizophrenia and 130 healthy volunteers. Sociodemographic characteristics, suicidal behavior, and symptom severity were assessed using data collection forms. Gene...

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Identifiers

PMID: 41663352
DOI: 10.1017/neu.2026.10058
PMCID: PMC13130374

Genes

LEPR
LEP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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