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Article

[Correlation between JAG1 ligand gene polymorphisms in the Notch signaling pathway and preeclampsia].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 28 Oct 2025

Xia Fan, Ye Changxiang, Jiang Yurong, Chen Lizhang, Wang Tingting

Abstract excerpt

OBJECTIVES: Preeclampsia (PE) is a clinical syndrome characterized by new-onset hypertension and proteinuria after 20 weeks of gestation, seriously affecting the short- and long-term health of both mothers and infants. The etiology and pathogenesis of PE remain incompletely understood. The Notch signaling pathway plays an important role in early upstream processes of PE, including trophoblast invasion and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41656810
DOI: 10.11817/j.issn.1672-7347.2025.250155
PMCID: PMC12949855

Genes

JAG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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