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Article

Baseline serum oxytocin and OXTR rs53576 genotype are not predictive of escitalopram response in generalized anxiety disorder.

Scientific reports - 5 Feb 2026

Xue Liang, Ni Hongfen, Xu Shuqi

Abstract excerpt

The oxytocin system is implicated in the pathophysiology of generalized anxiety disorder (GAD). However, its utility in predicting treatment outcomes with first-line antidepressants, such as escitalopram, remains unexplored. This study aimed to investigate whether baseline serum oxytocin levels and the oxytocin receptor gene polymorphism OXTR rs53576 can predict escitalopram response in patients with...

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Identifiers

PMID: 41644973
DOI: 10.1038/s41598-026-36366-9
PMCID: PMC12929608

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OXTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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