Article
Oxytocin receptor and G-protein polymorphisms in patients with depression and separation anxiety.
Journal of affective disorders - 15 Aug 2017
Costa Barbara, Pini Stefano, Baldwin David S, Silove Derrick, Manicavasagar Vijaya, Abelli Marianna, Coppedè Fabio, Martini Claudia
Abstract excerpt
BACKGROUND: The impact of combined variants of Oxytocin Receptor (OXTR) and G protein β3 subunit genes was investigated in relation to retrospective reports of childhood as well as contemporary adult separation anxiety (SA), based on evidence of a β/γ dimer-mediated signaling for OXTR. METHODS: A case-control association study (225 healthy adults and 188 outpatients with depression) was performed to establish...
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