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Article

Lack of influence of DAT1 and DRD2 gene variants on antidepressant response in generalized anxiety disorder.

Human psychopharmacology - 1 Jul 2014

Saung Wint Thu, Narasimhan Sneha, Lohoff Falk W

Abstract excerpt

OBJECTIVE: Although antidepressant drugs are used as first-line intervention to treat patients with generalized anxiety disorder (GAD), only one-third of patients respond positively to treatment. In our study, we investigated whether functional genetic polymorphisms in the dopamine active transporter 1 (DAT1) and dopamine receptor D2 (DRD2) may play a role in antidepressant treatment response in GAD. METHODS: We...

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Source

Identifiers

PMID: 24723432
DOI: 10.1002/hup.2404

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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