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Article

Genomic adaptation in group B Streptococcus following intrapartum antibiotic prophylaxis and childbirth.

mBio - 11 Mar 2026

Pell Macy E, Blankenship Heather M, Gaddy Jennifer A, Davies H Dele, Manning Shannon D

Abstract excerpt

Through vaginal colonization, group B Streptococcus (GBS) causes severe outcomes including neonatal sepsis and meningitis. Although intrapartum antibiotic prophylaxis (IAP) has reduced neonatal disease rates, GBS can persist in the genitourinary tract even after antibiotic administration. To determine if IAP selects for genomic signatures that enhance GBS survival and persistence, we compared the isolates from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41636481
DOI: 10.1128/mbio.03966-25
PMCID: PMC12977640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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