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Article

High-resolution genomics uncovers region-specific evolution and virulence of ocular Streptococcus pneumoniae.

Microbiology spectrum - 3 Mar 2026

Xiang Xi, Ye Mengke, Chen Shouyuan, Liu Lin, Hong Tingting, Hu Dongping, Ge Lihong, Fu Ying, Zhao Feng, Wang Yanfei, Bo Lihong, Lu Jun, Jiang Yan, Yu Yunsong, Wu Xueqing

Abstract excerpt

Streptococcus pneumoniae is the leading cause of sight-threatening ocular infection. However, comprehensive molecular epidemiological analyses that focus on ocular pneumococci are limited. We performed a high-resolution whole-genome analysis (WGS) of ocular pneumococcal isolates from the Zhejiang province of China and a global data set (n = 58). Using latex agglutination and the Quellung reaction, nine serotypes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41631845
DOI: 10.1128/spectrum.03291-25
PMCID: PMC12955406

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