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Article

HIF-1α is Associated with Improved Survival in Acute Respiratory Distress Syndrome due to COVID-19: A Prospective Study.

Nigerian journal of clinical practice - 1 Jan 2026

Sipahioglu H, Koyuncu S, Akalın H, Karasu N, Sipahioglu M H, Eren E E, Onuk S, Elay G, Saatci C, Yüksel R C, Gundogan K, Dundar M

Abstract excerpt

BACKGROUND: Acute respiratory distress syndrome (ARDS) due to coronovirus disease 2019 (COVID-19) is accompanied by severe hypoxemia and hyperinflammation. Hypoxia-inducible factor (HIF) pathway plays a fundamental role in detecting the hypoxia and developing appropriate responses. AIM: The aim of this study was to evaluate the role of HIF-1α and PHD2 (prolyl hydroxylase domain2) genes in the pathophysiology of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41631309
DOI: 10.4103/njcp.njcp_72_25

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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