Evolution on degenerate fitness landscapes is not random: Curvature drives directional drift.

Abstract excerpt

Degeneracy-the multiplicity of phenotypes with equal fitness-is a prevalent feature of biological systems. Such degeneracy is often associated with neutral evolution, under the assumption that adaptive dynamics on degenerate fitness manifolds is random and lacks direction. Here we show that this is not generally the case. Using a minimal model of evolutionary dynamics on smooth degenerate fitness landscapes, we...

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