Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of Change in Healthy Lifestyle in Early Adulthood With Steatotic Liver Disease Risk in Midlife.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Sept 2026

Chen Yun, Zhao Longgang, Mezzacappa Catherine, Steffen Lyn M, Carr John Jeffrey, Gao Tao, Terry James G, Qu Yishu, Bae Sejong, Taddei Tamar, Justice Amy C, Jacobs David R, Lloyd-Jones Donald M, Hou Lifang, Zhang Xuehong

Abstract excerpt

BACKGROUND & AIMS: Although benefits of healthy behaviors are well-recognized, it remains unclear whether change in healthy lifestyle in early adulthood influences steatotic liver disease (SLD) development in midlife, and to what extent genetic predisposition might modify these associations. METHODS: In the Coronary Artery Risk Development in Young Adults (CARDIA) study, we constructed a healthy lifestyle score...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Fatty Liver

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PNPLA3 gene

Share to Genetic Predisposition to Disease

Share to Healthy Lifestyle

Share to Tomography, X-Ray Computed

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 41620192
DOI: 10.1016/j.cgh.2026.01.019
PMCID: PMC13097063

Genes

PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of Change in Healthy Lifestyle in Early Adulthood With Steatotic Liver Disease Risk in Midlife.PMID 41620192Read ↗

Modifiable lifestyle factors, genetic and acquired risk, and the risk of severe liver disease in the UK Biobank cohort: (Lifestyle factors and SLD).Semantic proximity Read ↗

Genetic risk amplifies lifestyle effects on hepatic steatosis and its progression: Insights from a population-based cohort.Semantic proximity Read ↗

Sleep patterns, genetic predisposition, and risk of chronic liver disease: A prospective study of 408,560 UK Biobank participants.Semantic proximity Read ↗

Longitudinal changes in fatty liver index, genetic susceptibility, and incident atrial fibrillation.Semantic proximity Read ↗

Genetic risk, adherence to healthy lifestyle behaviors, and risk of cholelithiasis: A population-based cohort study.Semantic proximity Read ↗

Healthy Lifestyle including Sleep Patterns, Genetic Risk, and Risk of Cardiometabolic MultimorbiditySemantic proximity Read ↗

An Invisible Early Steatosis Phenotype Defined for a Large Population-Based CohortSemantic proximity Read ↗

Association of non-high-density lipoprotein cholesterol trajectories with the development of non-alcoholic fatty liver disease: an epidemiological and genome-wide association studySemantic proximity Read ↗

Healthy lifestyle for the prevention of post-COVID-19 multisystem sequelae, hospitalization, and death: a prospective cohort studySemantic proximity Read ↗

Healthy Sleep Patterns, Genetic Susceptibility, and Incident of Cirrhosis and Liver CancerSemantic proximity Read ↗

American Heart Association's Life's Simple 7: Lifestyle Recommendations, Polygenic Risk, and Lifetime Risk of Coronary Heart Disease.Semantic proximity Read ↗

Improved Diet Quality Associates With Reduction in Liver Fat, Particularly in Individuals With High Genetic Risk Scores for Nonalcoholic Fatty Liver Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.