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Metagenomic Analysis of Bronchoalveolar Lavage Fluid Enables Differential Diagnosis Between Lung Cancer and Pulmonary Infections

2024-02-09

Abstract excerpt

<title>Abstract</title> <p>Recent advances in unbiased metagenomic next-generation sequencing (mNGS) have enabled the simultaneous examination of both microbial and host genetic material in a single test. This study harnesses cost-effective bronchoalveolar lavage fluid (BALF) mNGS data from patients with lung cancer (n=123) and pulmonary infections (n=279). We developed a machine learning-based diagnostic approac...

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Literature Corpus work
7c2db924-6633-52e2-9db6-5c6c133cca40
DOI
10.21203/rs.3.rs-3883914/v1
Open publication

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