Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Geographic spillover of antimicrobial resistance from mass distribution of azithromycin.

Nature communications - 29 Jan 2026

Srivathsan Ariktha, Arzika Ahmed M, Maliki Ramatou, Abdou Amza, Lipsitch Marc, Blumberg Seth, O'Brien Kieran S, Porco Travis C, Hinterwirth Armin, Doan Thuy, Keenan Jeremy D, Lietman Thomas M, Arnold Benjamin F

Abstract excerpt

Large-scale, placebo-controlled, cluster-randomized trials in high-mortality settings in sub-Saharan Africa demonstrated a 14-18% reduction in childhood mortality following twice-annual mass drug administration (MDA) of azithromycin among children aged 1-59 months. Azithromycin MDA also selected for antimicrobial resistance (AMR), particularly macrolide resistance. It is unknown whether the AMR from azithromycin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Azithromycin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Drug Resistance, Bacterial

Share to Genotype

Share to Geography

Share to Infant

Share to Macrolides

Source

Open in PubMed Open full text

Identifiers

PMID: 41611691
DOI: 10.1038/s41467-026-68691-y
PMCID: PMC12957345

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 11 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Geographic spillover of antimicrobial resistance from mass distribution of azithromycin.PMID 41611691Read ↗

Macrolide and non-macrolide resistance after 36 months of mass azithromycin distribution in Burkina Faso: A cluster randomized trialSemantic proximity Read ↗

Targeting community-level drivers of antimicrobial resistance in sub-Saharan Africa: the effect of a community-based intervention bundle on household transmission of Extended Spectrum Beta-lactamase-producing <i>E. coli</i> in rural Burkina Faso - a cluster randomised trialSemantic proximity Read ↗

Impact of intra-partum Azithromycin on carriage of group A streptococcus in The Gambia: a posthoc analysis of a double-blind randomized placebo-controlled trialSemantic proximity Read ↗

Pharmacokinetics and pharmacodynamics of azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a protocol for a Phase II randomised controlled trialSemantic proximity Read ↗

Community-level Monitoring of Antimicrobial Resistance following Mass Administration of Azithromycin to Reduce Child Mortality in Côte d’Ivoire: Results from Two Rounds of SurveillanceSemantic proximity Read ↗

Using transportability methods to map the local effectiveness of mass drug administration for malaria in SenegalSemantic proximity Read ↗

Impact of control interventions on malaria incidence in the general population of MaliSemantic proximity Read ↗

FocaL mass drug Administration for Plasmodium vivax Malaria Elimination (FLAME): study protocol for an open-label cluster randomized controlled trial in PeruSemantic proximity Read ↗

Implementation of mass drug administration of antibiotics in low- and middle- income countriesSemantic proximity Read ↗

Community benefits of mass distribution of three types of dual-active-ingredient long-lasting insecticidal nets against malaria prevalence in Tanzania: evidence from a 3-year cluster-randomized controlled trialSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.