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Pharmacokinetics and pharmacodynamics of azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a protocol for a Phase II randomised controlled trial

2023-01-10

Abstract excerpt

<h4>Background: </h4> African children with severe malaria are susceptible to Gram-negative bacterial co-infection, largely non-typhoidal Salmonellae, leading to a substantially higher rates of in-hospital and post-discharge mortality than those without bacteraemia. Current evidence for treating co-infection is lacking, and there is no consensus on the dosage or length of treatment required. We therefore aimed to...

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Literature Corpus work
6f835d7a-7b70-535a-a5a3-e1323b1723a5
DOI
10.12688/wellcomeopenres.16968.2
Open publication

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Pharmacokinetics and pharmacodynamics of azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a protocol for a Phase II randomised controlled trialDOI 10.12688/wellcomeopenres.16968.2
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