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Targeting community-level drivers of antimicrobial resistance in sub-Saharan Africa: the effect of a community-based intervention bundle on household transmission of Extended Spectrum Beta-lactamase-producing <i>E. coli</i> in rural Burkina Faso - a cluster randomised trial

2025-12-16

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> In sub-Saharan Africa (sSA), invasive antimicrobial-resistant infections often originate from community-level acquisition. We assessed whether a behavioural intervention bundle targeting sub-optimal antibiotic use and hygiene practices reduced household-level acquisition of extended-spectrum beta-lactamase–producing E. coli (ESBL-E). <h4>Methods</h4> We conducted a cluster...

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Literature Corpus work
bec616f3-f42c-50d2-9a13-d70ce17d695e
DOI
10.64898/2025.12.15.25342269
Open publication

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Targeting community-level drivers of antimicrobial resistance in sub-Saharan Africa: the effect of a community-based intervention bundle on household transmission of Extended Spectrum Beta-lactamase-producing <i>E. coli</i> in rural Burkina Faso - a cluster randomised trialDOI 10.64898/2025.12.15.25342269
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