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Endotyping in Chronic Rhinosinusitis-An EAACI Task Force Report.

Allergy - 1 Jan 2025

Toppila-Salmi Sanna, Reitsma Sietze, Hox Valérie, Gane Simon, Eguiluz-Gracia Ibon, Shamji Mohamed, Maza-Solano Juan, Jääskeläinen Benjamin, Väärä Risto, Escribese Maria M, Chaker Adam, Karavelia Aspasia, Rudenko Michael, Gevaert Philippe, Klimek Ludger

Abstract excerpt

Chronic rhinosinusitis (CRS) is a clinical syndrome defined by typical sinonasal symptoms persisting for at least 12 weeks. CRS is divided into two distinct phenotypes, CRS with nasal polyps (CRSwNP) and without (CRSsNP). The aim of the review is to provide an update on the current knowledge in CRS endotypes. The prevailing hypothesis regarding the pathogenesis of CRS suggests that dysfunctional interactions...

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PMID: 39641584
DOI: 10.1111/all.16418
PMCID: PMC11724251

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