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Article

The role of miR-199a-3p in a benzo[a]pyrene-induced cross-generational bone phenotype in Japanese medaka (Oryzias latipes).

Environmental toxicology and chemistry - 1 May 2026

Jayarajan Rijith, Martin Leisha, Trujillo Alexis, Labeille Remi, Seemann Frauke

Abstract excerpt

Benzo[a]pyrene (BaP), a ubiquitous environmental pollutant and known carcinogen, has been shown to disrupt transgenerational bone development via epigenetic mechanisms, including microRNAs (miRNAs). Among these, miR-199a-3p has emerged as a quintessential regulator in transcriptomic analyses of bone tissue from ancestrally BaP-exposed F3 generation medaka fish, with significant enrichment in bone formation and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41604315
DOI: 10.1093/etojnl/vgag025
PMCID: PMC13183762

Genes

F3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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