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Article

The association between interatrial shunt and subtypes of migraine: a Mendelian randomization study.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 27 Jan 2026

Che Xiaona, Qi Xin, Kong Ziang, Li Xinqi, Na Lin, Sun Yunfei, Cui Wenjing, Chang Jing, Xue Xin

Abstract excerpt

BACKGROUND: Approximately one-quarter of adults have a patent foramen ovale (PFO). Migraine is the second most prevalent neurological disorder. The potential causal relationship between PFO and migraine has been a subject of ongoing debate. This study aims to investigate the genetic association between PFO and migraine. MATERIALS AND METHODS: This study utilized aggregated data from the Finnish database to...

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Identifiers

PMID: 41591511
DOI: 10.1007/s10072-025-08778-4
PMCID: PMC12847208

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