Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The research potential of A20 in psoriatic arthritis.

Frontiers in immunology - 1 Jan 2025

Wan Yixuan Wang, Duan Xiaoru, Jin Zilin, Chen Hongxiang

Abstract excerpt

Psoriasis, a systemic inflammatory disorder, extends beyond its classical dermatological presentation to encompass multiple manifestations including arthritis, inflammatory bowel disease, ocular inflammation (conjunctivitis/uveitis), and cardiovascular manifestations such as aortic valve pathology. While cutaneous manifestations have been extensively characterized, psoriatic arthritis (PsA) remains challenging to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Psoriatic
Share to Disease Models, Animal
Share to TNFAIP3 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to NF-kappa B

Share to Signal Transduction

Share to Tumor Necrosis Factor alpha-Induced Protein 3

Source

Open in PubMed Open full text

Identifiers

PMID: 41583484
DOI: 10.3389/fimmu.2025.1630198
PMCID: PMC12827524

Genes

TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The research potential of A20 in psoriatic arthritis.PMID 41583484Read ↗

Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimmune disease.Semantic proximity Read ↗

Single nucleotide polymorphisms at the TNFAIP3/A20 locus and susceptibility/resistance to inflammatory and autoimmune diseases.Semantic proximity Read ↗

Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis.Semantic proximity Read ↗

The Ubiquitin System and A20: Implications in Health and DiseaseSemantic proximity Read ↗

Non-catalytic ubiquitin binding by A20 prevents psoriatic arthritis-like disease and inflammation.Semantic proximity Read ↗

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease.Semantic proximity Read ↗

Overview of the molecular determinants contributing to the expression of Psoriasis and Psoriatic Arthritis phenotypes.Semantic proximity Read ↗

A20 in inflammation and autoimmunity.Semantic proximity Read ↗

Preserving immune homeostasis with A20.Semantic proximity Read ↗

Genetic Variants of the NF-κB Pathway: Unraveling the Genetic Architecture of Psoriatic Disease.Semantic proximity Read ↗

Etiology and Pathogenesis of Psoriatic Arthritis.Semantic proximity Read ↗

The Molecular Pathophysiology of Psoriatic Arthritis—The Complex Interplay Between Genetic Predisposition, Epigenetics Factors, and the MicrobiomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.