Article
Assessing cross-transmission of Gram-negative bacteria in the intensive care unit: a prospective comparison of IR-Biotyper and core-genome multi-locus sequence typing.
The Journal of hospital infection - 1 Apr 2026
Villa A, Danjean M, Sakr C, Cizeau F, Ducellier D, N'Debi M, Mekontso-Dessap A, Razazi K, Decousser J-W
Abstract excerpt
BACKGROUND: Healthcare-associated infections are a major concern in intensive care units (ICUs), where early detection of transmission cluster is critical. Whole-genome sequencing remains the reference method for outbreak investigation but is limited by cost and turnaround time. The IR Biotyper (IRBT) provides rapid phenotypic clustering, but its core-genome-level performance remains insufficiently evaluated....
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