Article
A genome-wide association study of adults with community-acquired pneumonia.
Respiratory research - 16 Oct 2024
Suarez-Pajes Eva, Marcelino-Rodriguez Itahisa, Hernández Brito Elisa, Gonzalez-Barbuzano Silvia, Ramirez-Falcon Melody, Tosco-Herrera Eva, Rubio-Rodríguez Luis A, Briones María Luisa, Rajas Olga, Borderías Luis, Ferreres Jose, Payeras Antoni, Lorente Leonardo, Aspa Javier, Lorenzo Salazar Jose M, Valencia-Gallardo José Manuel, Carbonell Nieves, Freixinet Jorge L, Rodríguez de Castro Felipe, Solé Violán Jordi, Flores Carlos, Rodríguez-Gallego Carlos
Abstract excerpt
BACKGROUND: Community-acquired pneumonia (CAP) is associated with high morbidity and hospitalization rate. In infectious diseases, host genetics plays a critical role in susceptibility and immune response, and the immune pathways involved are highly dependent on the microorganism and its route of infection. Here we aimed to identify genetic risk loci for CAP using a case-control genome-wide association study...
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