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Article

Whole-Exome Profiling of Epstein-Barr Virus-Positive Neuroendocrine Carcinoma of the Nasopharynx.

Endocrine pathology - 24 Jan 2026

Chen Xin-Chun, Fu Jian-Chang, Zhang Ao, Liu Yuan-Tao, Xing Shan, Wang Fang, Zhang Xiao-Ying, Kong Xiang-Wei, Li Yan

Abstract excerpt

Epstein-Barr virus (EBV)-positive neuroendocrine carcinoma (NEC) of the nasopharynx is a rare malignancy with poor prognosis and lacks squamous markers, rendering it biologically distinct from nasopharyngeal carcinoma (NPC) of squamous epithelial origin. However, its molecular features remain largely undefined, and the entity has not been formally recognized as a nasopharyngeal carcinoma subtype, substantially...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41579269
DOI: 10.1007/s12022-026-09902-6

Genes

TP53
APC
KMT2A
PROK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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