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Oxidative Balance Score, Genetic Predictors of the Gut Microbiome, and the Risk of Metabolic-Associated Fatty Liver Disease: A Cohort Study.

Molecular nutrition & food research - 1 Jan 2026

Ji Xiang, Wang Yawen, Li Liuxin, Yang Honghao, Ma Zheng, Wang Chenying, Zhao Yuhong, Ding Yang, Xia Yang

Abstract excerpt

The oxidative balance score (OBS) integrates dietary and lifestyle factors to reflect oxidative stress. OBS has been associated with metabolic dysfunction-associated steatotic liver disease (MASLD), but the modifying roles of genetic predisposition and gut microbiota remain unclear. This study evaluated the prospective association between OBS and MASLD and potential modification by genetic and microbial factors....

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PMID: 41543287
DOI: 10.1002/mnfr.70372

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