Clinical subphenotypes of sepsis based on mixed continuous and categorical data and differences in treatment effects: a cluster analysis of multicenter observational studies.

Abstract excerpt

BACKGROUND: Sepsis is a heterogeneous syndrome; therefore, identifying subphenotypes is essential to determine the optimal treatment for each patient. Previous studies have mainly analyzed continuous variables and focused on the treatment effects in patient cohorts receiving a single intervention. In this study, we explored subphenotypes using mixed continuous and categorical data and examined multiple treatment...

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• Aged
• Cluster Analysis
• Clustering Algorithms
• Intensive Care Units
• Japan