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Article

Prevalence, clinical and molecular characteristics of early stage EGFR-mutated lung cancer in a real-life West-European cohort: Implications for adjuvant therapy.

European journal of cancer (Oxford, England : 1990) - 1 Mar 2023

Hondelink Liesbeth M, Ernst Sophie M, Atmodimedjo Peggy, Cohen Danielle, Wolf Janina L, Dingemans Anne-Marie C, Dubbink Hendrikus J, von der Thüsen Jan H

Abstract excerpt

OBJECTIVES: The landmark ADAURA study recently demonstrated a significant disease-free survival benefit of adjuvant osimertinib in patients with resected EGFR-mutated lung adenocarcinoma. However, data on prevalence rates and stage distribution of EGFR mutations in non-small cell lung cancer in Western populations are limited since upfront EGFR testing in early stage lung adenocarcinoma is not common practice....

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PMID: 36638752
DOI: 10.1016/j.ejca.2022.12.010

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