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Article

Surgical resection versus stereotactic radiosurgery for succinate dehydrogenase-related hereditary head and neck paragangliomas.

Journal of neuro-oncology - 14 Jan 2026

Harary Paul M, Hori Yusuke S, Lam Fred C, Abu-Reesh Deya, Emrich Sara C, Tayag Armine, Ustrzynski Louisa, Alyono Jennifer, Holsinger F Christopher, Dodd Robert L, Gibbs Iris C, Li Gordon, Park David J, Chang Steven D

Abstract excerpt

PURPOSE: Succinate dehydrogenase (SDH) mutations are strongly associated with head and neck paraganglioma (HN-PGL), with recent evidence suggesting differences in tumor behavior relative to sporadic lesions. However, the optimal treatment strategy for this population remains unclear. We therefore compared the efficacy of surgical resection versus stereotactic radiosurgery (SRS) in patients with SDH-mutant HN-PGL....

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Identifiers

PMID: 41533247
DOI: 10.1007/s11060-025-05405-2

Genes

SDHD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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