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Article

Malignant head and neck paragangliomas in SDHB mutation carriers.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 Jul 2007

Boedeker Carsten Christof, Neumann Hartmut P H, Maier Wolfgang, Bausch Birke, Schipper Jörg, Ridder Gerd Jürgen

Abstract excerpt

OBJECTIVE: Three of four paraganglioma syndromes (PGLs) have been characterized on a molecular genetic basis. PGL 1 is associated with mutations of the succinate dehydrogenase subunit D (SDHD) gene, PGL 3 is caused by SDHC gene mutations, and PGL 4 is caused by SDHB gene mutations. The objective of this study was to investigate whether PGLs are associated with malignant head and neck paragangliomas (HNPs). STUDY...

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Source

Identifiers

PMID: 17599579
DOI: 10.1016/j.otohns.2007.01.015

Genes

SDHB
SDHC
SDHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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