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Article

Analysis of molecular subtypes and prognostic signature of senescence-associated secretory phenotype in pancreatic cancer.

PeerJ - 1 Jan 2026

Kuang Yuewen, Jia Mingkun, Zhu Yuming, Xiang Zhiyong

Abstract excerpt

Background: Pancreatic cancer (PC) exhibits an extremely poor prognosis due to its high heterogeneity. The senescence-associated secretory phenotype (SASP), a distinct secretory profile displayed by senescent cells, has been increasingly studied. However, the role of SASP in PC prognosis and treatment remains unclear. Methods: Transcriptomic sequencing data from PC patients were analyzed using consensus...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41522514
DOI: 10.7717/peerj.20476
PMCID: PMC12786131

Genes

PC
ANGPTL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

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