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Article

Development and Verification of the Hypoxia- and Immune-Associated Prognostic Signature for Pancreatic Ductal Adenocarcinoma.

Frontiers in immunology - 1 Jan 2021

Chen Dongjie, Huang Hui, Zang Longjun, Gao Wenzhe, Zhu Hongwei, Yu Xiao

Abstract excerpt

We aim to construct a hypoxia- and immune-associated risk score model to predict the prognosis of patients with pancreatic ductal adenocarcinoma (PDAC). By unsupervised consensus clustering algorithms, we generate two different hypoxia clusters. Then, we screened out 682 hypoxia-associated and 528 immune-associated PDAC differentially expressed genes (DEGs) of PDAC using Pearson correlation analysis based on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34691034
DOI: 10.3389/fimmu.2021.728062
PMCID: PMC8526937

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