Article
Discerning the HLA allele and haplotype frequencies in the multiethnic population of Malaysia.
Human immunology - 1 Feb 2026
Kevin-Tey Wen Fei, Wen Sean, Chong Ho Phin, Bee Ping Chong, Mohd Zain Shamsul, Mohamad Mardziah, Mohamed Yusoff Nisya, Eng Hooi Sian, Lim Soo Kun, Tan Sen Mui, Jalalonmuhali Maisarah
Abstract excerpt
The human leukocyte antigen (HLA) system is central to immune function, transplantation compatibility, and disease susceptibility. However, comprehensive data on HLA allele and haplotype distributions in Southeast Asia, particularly Malaysia, remain limited despite the region's rich genetic diversity. In this study we analyzed HLA class I (A, B, C) and class II (DRB1, DQB1) alleles in 4,882 individuals of Malay,...
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