Article
HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 951 Southeast Asia Malays from Peninsular Malaysia.
Human immunology - 1 Oct 2016
Tan Lay-Kim, Mohd-Farid Baharin, Salsabil Sulaiman, Heselynn Hussein, Wahinuddin Sulaiman, Lau Ing-Soo, Gun Suk-Chyn, Nor-Suhaila Sharil, Eashwary M, Mohd-Shahrir Mohamed Said, Ainon Mohd-Mokhtar, Azmillah Rosman, Muhaini Othman, Shahnaz Murad, Too Chun-Lai
Abstract excerpt
A total of 951 Southeast Asia Malays from Peninsular Malaysia were genotyped for HLA-A, -B, -C -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, there were significant deviation from Hardy-Weinberg proportions for the HLA-A (p<0.0001), -B (p<0.0001), -DRB1 (p<0.0001) and -DQB1 (p<0.01) loci. Minor deviations from HWEP were detected...
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