Article
HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 271 Southeast Asia Indians from Peninsular Malaysia.
Human immunology - 1 Jun 2020
Nurul-Aain Ahmad Fauzi, Tan Lay-Kim, Heselynn Hussein, Nor-Shuhaila Shahril, Eashwary Mageswaran, Wahinuddin Sulaiman, Lau Ing Soo, Gun Suk Chyn, Mohd-Shahrir Mohamed-Said, Ainon Mohd-Mokhtar, Azmillah Rosman, Muhaini Othman, Shahnaz Murad, Too Chun-Lai
Abstract excerpt
A total of 271 Southeast Asia Indians from Peninsular Malaysia were genotyped for HLA-A, -B, -C, -DRB1, and -DQB1 loci using polymerase chain reaction sequence-specific oligonucleotide probe hybridization methods. In this report, HLA-B and HLA-DQB1 was in Hardy-Weinberg proportions (HWEP) (p > 0.05). We observed significant deviation from the HWEP for HLA-A (p < 0.05), HLA-C (p < 0.01) and HLA-DRB1 (p < 0.01)...
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