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Article

T2/FLAIR Mismatch Subregion as an Independent Prognostic Biomarker in IDH-Mutant and 1p/19q Noncodeletion Astrocytoma.

AJNR. American journal of neuroradiology - 3 Jun 2026

Xing Zhen, Yu Lan, Yu Shujie, Yu Feifei, Lin Xiaoye, Wang Feng, Zhou Xiaofang, Cai Jiawei, Cao Dairong, Kang Dezhi

Abstract excerpt

BACKGROUND AND PURPOSE: While the global T2/FLAIR mismatch sign is a diagnostic hallmark of IDH-mutant and 1p/19q noncodeletion astrocytoma, the prognostic significance of partial mismatch patterns remains unclear. This study investigated the differences in MRI between subregions with a T2/FLAIR mismatch and a match, and the impact of these differences on astrocytoma clinical outcomes. MATERIALS AND METHODS: This...

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Identifiers

PMID: 41506844
DOI: 10.3174/ajnr.A9158
PMCID: PMC13232656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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