Article
Diffusion MRI is superior to quantitative T2-FLAIR mismatch in predicting molecular subtypes of human non-enhancing gliomas.
Neuroradiology - 1 Dec 2024
Cho Nicholas S, Sanvito Francesco, Le Viên Lam, Oshima Sonoko, Teraishi Ashley, Yao Jingwen, Telesca Donatello, Raymond Catalina, Pope Whitney B, Nghiemphu Phioanh L, Lai Albert, Salamon Noriko, Cloughesy Timothy F, Ellingson Benjamin M
Abstract excerpt
PURPOSE: This study compared the classification performance of normalized apparent diffusion coefficient (nADC) with percentage T2-FLAIR mismatch-volume (%T2FM-volume) for differentiating between IDH-mutant astrocytoma (IDHm-A) and other glioma molecular subtypes. METHODS: A total of 105 non-enhancing gliomas were studied. T2-FLAIR digital subtraction maps were used to identify T2FM and T2-FLAIR non-mismatch...
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