The investigation of molecular epidemiological characteristics and resistance mechanism of tigecycline resistant Klebsiella pneumoniae from a large teaching hospital in southwest China, Chongqing.

doi:10.3389/fcimb.2025.1540967

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Article

The investigation of molecular epidemiological characteristics and resistance mechanism of tigecycline resistant Klebsiella pneumoniae from a large teaching hospital in southwest China, Chongqing.

Frontiers in cellular and infection microbiology - 1 Jan 2025

Li Yuqiong, Tang Shiyu, Han Qi, Xia Peiwen, Si Tingting, Song Yuanyuan, Xia Yun

Abstract excerpt

Background: Klebsiella pneumoniae is one of the main pathogens of nosocomial infection, among which carbapenems can be used for multidrug-resistant Klebsiella pneumoniae. However, in the past decade, the resistance rate of carbapenem-resistant Klebsiella pneumoniae has increased yearly. Tigecycline has good antibacterial activity in treating severe bacterial infections, but the reports of tigecycline resistance...

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Topics

Klebsiella pneumoniae
Tigecycline
China
Hospitals, Teaching
Humans
Klebsiella Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Anti-Bacterial Agents

Microbial Sensitivity Tests

Bacterial Proteins

Molecular Epidemiology

Drug Resistance, Multiple, Bacterial

Drug Resistance, Bacterial

Mutation

Membrane Transport Proteins

Source

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Identifiers

PMID: 40182765
DOI: 10.3389/fcimb.2025.1540967
PMCID: PMC11965929

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