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Oropharyngeal Microbiota Clusters in Children with Asthma or Wheeze Associate with Allergy, Blood Transcriptomic Immune Pathways, and Exacerbation Risk

10 May 2023

Abstract excerpt

Abstract Rationale Children with preschool wheezing or school-age asthma are reported to have airway microbial imbalances. Objectives To identify clusters in children with asthma or wheezing using oropharyngeal microbiota profiles. Methods Oropharyngeal swabs from the U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes) pediatric asthma or wheezing cohort were characterized using 16S...

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PMID: 37163754
DOI: 10.1164/rccm.202211-2107oc

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