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Article

Blastic Plasmacytoid Dendritic Cell Neoplasm With De Novo TET2 and KDM6A Mutations.

Journal of cutaneous pathology - 1 Apr 2026

Qiu Zixin, Tong Jianbo, Wan Chuan, Cao Xianwei, Zhang Zhibin

Abstract excerpt

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, highly aggressive hematologic malignancy characterized by cutaneous involvement with potential dissemination to peripheral blood, bone marrow, lymph nodes, or extranodal sites. We present the first documented case of BPDCN exhibiting complex epigenetic dysregulation in a 54-year-old female who developed rapidly progressive purpuric lesions on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41482477
DOI: 10.1111/cup.70050

Genes

KDM6A
TET2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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