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Article

The genetics and screening of familial hypercholesterolaemia

16 Apr 2016

Abstract excerpt

Familial Hypercholesterolaemia is an autosomal, dominant genetic disorder that leads to elevated blood cholesterol and a dramatically increased risk of atherosclerosis. It is perceived as a rare condition. However it affects 1 in 250 of the population globally, making it an important public health concern. In communities with founder effects, higher disease prevalences are observed.We discuss the genetic basis of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27084339
DOI: 10.1186/s12929-016-0256-1

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